Brian M. Isern is the founder and manager of Sibling Consulting, LLC, which advises private market companies on business development, as well as financial and capital raising strategies, across various sectors.  Mr. Isern is also managing member of Sibling Capital Holdings LLC, an investment holding company focused on alternative assets across various sectors. 

Mr. Isern was previously co-founder and president of Sibling Capital Ventures LLC and Sibling Capital, LLC, life science-focused venture capital firms.  Since the firm’s founding in 2012, Isern led various financing rounds totaling over $50 million in biotech investments.  Isern helped lead Sibling Capital’s participation in the Series C financing for Relypsa, Inc. in 2012, which proceeded to an initial public offering in 2013 and FDA approval for its lead drug, Veltassa, to treat hyperkalemia in 2015.  Relypsa was then acquired by Galenica for $1.53 billion in 2016.  Additionally, in 2013, Isern led Sibling Capital’s seed investment in Tricida, Inc., whose lead drug, Veverimer, was a non-absorbed, orally administered polymer designed to treat metabolic acidosis in patients with chronic kidney disease (CKD).  Isern then led Sibling Capital’s additional investments in several financing rounds for Tricida, Inc., which ultimately proceeded to an initial public offering in 2018.

Prior to founding Sibling and co-founding Sibling Capital, Mr. Isern worked in the investment banking department of Global Hunter Securities LLC (currently known as Seaport Global).  Prior to Global Hunter Securities and while attending business school, he was an investment research manager with Tulane University’s equity research program, Burkenroad Reports.  He was a recipient of the Morton A. Aldrich Fellowship and received his MBA from Tulane University’s A. B. Freeman School of Business with a concentration in finance and specialization in energy, and previously served on Freeman’s Business School Council.  He graduated in 2004 with a Bachelor of Arts in communication from the University of Alabama, where he was a student athlete on the men’s tennis team.